01.002 RWE KR June 2022 G 07-07-2022

Emulating control arms for oncology clinical trials using real-world data

  • Trial data was used from published control arm results from 15 trials that supported drug approvals from January 1, 2016, to April 30, 2018
  • RWD cohorts were constructed using a nationwide EHR-derived de-identified database by aligning eligibility criteria and weighting to trial baseline characteristics
  • The trial data and RWD cohorts were compared using Kaplan–Meier and Cox proportional hazards regression models
  • EHR-derived RWD can emulate oncology clinical trial control arm results, although with variability
Click here to learn more.

About SVMPharma

SVMPharma is an innovative strategic consultancy and CRO, with a focus in Real World Evidence (RWE) for pharmaceutical and biotechnology companies. SVMPharma delivers clinical trials within UK and Europe.


DISTILL is a new EDC launched by SVMPharma. As a CRO discover the benefits of DISTILL as part of your service offering and take back control of your clinical trials. DISTILL allows you to develop and manage every aspect of your trials from start to finish. Move away from the restrictions and costs associated with legacy systems.

For more information, please visit and contact us at